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Recombinant Spike RBD Protein of SARS-CoV-2 Brazil Variant
Recombinant Spike RBD Protein of SARS-CoV-2 Brazil Variant
- 中文名称：
- Recombinant Spike RBD Protein of SARS-CoV-2 Brazil Variant
- 英文名称：
- Recombinant Spike RBD Protein of SARS-CoV-2 Brazil Variant
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA62224
- 规格：
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议：
- Store at -20°C. Stable for 3 months from the date of shipment when kept at 4°C. Non-hazardous, no MSDS required.
- 货期：
- 6-8周
- 纯度：
- > 95% (by SDS-PAGE)
- 产品形式：
- N/A
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: Recombinant spike RBD (K417T, E484K, N501Y) protein of SARS-CoV-2 Brazil variant (B.1.1.248) expressed and purified from HEK293 cells. The binding activity has been tested using human ACE2 protein in a functional ELISA assay.
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS?CoV?2) is the virus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. Many SARS-CoV-2 variants have been identified throughout the world since it’s outbreak in late 2019; some are believed or have been believed to be of particular importance due to their potential for increased transmissibility, increased virulence, and reduced effectiveness of vaccines against them.
The genome of SARS-CoV-2 has 89% nucleotide identity with bat SARS-like-CoVZXC21 and 82% with that of human SARS-CoV. The phylogenetic trees of their orf1a/b, Spike, Envelope, Membrane and Nucleoprotein also clustered closely with those of the bat, civet and human SARS coronaviruses. However, the external subdomain of Spike's receptor binding domain (RBD) of SARS-CoV-2 shares only 40% amino acid identity with other SARS-related coronaviruses.
