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Human Transmembrane Protease, Serine 2 (TMPRSS-2) Stable Cell Line
Human Transmembrane Protease, Serine 2 (TMPRSS-2) Stable Cell Line
- 中文名称：
- Human Transmembrane Protease, Serine 2 (TMPRSS-2) Stable Cell Line
- 英文名称：
- Human Transmembrane Protease, Serine 2 (TMPRSS-2) Stable Cell Line
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA62236
- 规格：
- INQUIRE
- 保存建议：
- Remove the frozen cells from the dry ice packaging and immediately place the cells at a temperature below -130 degree C, preferably in liquid nitrogen vapor, until ready for use.
Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Stable ACE2-TMPRSS2 cells: 1 mL (2 x 10^6 cells/mL in DMEM, 10% FBS, 10% DMSO)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
This HEK293-hTMPRSS2-hACE2 stable cell line expresses a recombinant human Transmembrane Protease, Serine 2 (TMPRSS-2) and a human Angiotensin-Converting Enzyme 2 (ACE2). It can be used for drug screening and for studying SARS-CoV-2 viral entry.
The TMPRSS2 gene encodes a protein that belongs to the serine protease family. The encoded protein, Transmembrane Protease, Serine 2, contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). The ACE2, Angiotensin-Converting Enzyme 2, is the main receptor protein for SARS-CoV-2 Spike protein
