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Sorbent for anti-cross-reactive carbohydrate determinants (CCD) antibodies
Sorbent for anti-cross-reactive carbohydrate determinants (CCD) antibodies
- 中文名称：
- Sorbent for anti-cross-reactive carbohydrate determinants (CCD) antibodies
- 英文名称：
- Sorbent for anti-cross-reactive carbohydrate determinants (CCD) antibodies
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA72875
- 规格：
- 1 mg|2x1 mg|3x1 mg|4x1 mg|5x1 mg
- 保存建议：
- Sorbent is shipped at room temperature. Upon arrival, it should be stored at 4° to -20°C in vertical position, avoiding all possible humidity and maintaining the vials dry. Once reconstituted, it should be aliquoted to avoid repeated freezing and thawing cycles and stored at -20ºC to -80ºC.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- dry powder (stabilized with 5% trehalose)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
solution of several glycoconjugates.
Cross-reactive carbohydrate determinants (CCD) are glycan structures attached to proteins during post-translational modifications. In addition to the CCD structures of glycosylated proteins from plants or invertebrates, which are immunogenic (as they differ from those of human glycoproteins), there are also glycoproteins from several yeast species which have adapted to colonize human tissue. One example is the endo-saprophytic yeast Candida albicans, which can invade human tissues in immunosuppressed patients, leading to frequent nosocomial systemic infections. Among these virulence attributes critical for survival under changing environmental conditions, is the yeast cell wall containing large amounts of carbohydrates and carbohydrates covalently linked to a noncarbohydrate moiety classified as glycoconjugates, either glycoproteins or glycolipids. Despite similarities in the early steps of processing, the mature structure of glycans differs substantially between yeasts and mammals. Depending on the species, fungal high mannose glycans contain distinctive modifications, such as the addition of mannosyl phosphate and beta-linked mannose. These IgG antibodies against the ?-linked mannose are frequently present among healthy individuals without regard to age, race, or gender.
