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STAT4 recombinant protein
STAT4 recombinant protein
- 中文名称：
- STAT4 recombinant protein
- 英文名称：
- STAT4 recombinant protein
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA72890
- 规格：
- 0.02 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >95%
- 产品形式：
- 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant full-length human STAT4 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.
Scientific Background: STAT4 (signal transducer and activator of transcription 4) is a member of the STAT family that is phosphorylated by receptor-associated protein kinases. STATs form homo- or heterodimers and translocate to the cell nucleus where they act as transcription activators. T helper (Th) cells differentiation is regulated by STAT4 (1). STAT4 controls T1/T2 balance during the response to live influenza virus and isolated viral proteins. The differentiation of gamma interferon (IFN-gamma)-producing Th1 and Tc1 cells after inoculation of live virus occurred independently of STAT4 expression. STAT4 has been shown to control pathogenesis of chronic obstructive pulmonary disease (2).
