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MLL1 (KMT2A), Active
MLL1 (KMT2A), Active
- 中文名称:
- MLL1 (KMT2A), Active
- 英文名称:
- MLL1 (KMT2A), Active
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA73021
- 规格:
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议:
- Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Stable for 1 year at -70°C from date of receipt.
- 货期:
- 6-8周
- 纯度:
- > 90%
- 产品形式:
- Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Recombinant human MLL1 (3738-end ) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The MLL1 (KMT2A) protein accession number is NM_005933.
Scientific Background: Histone-lysine N-methyltransferase 2A also known as mixed-lineage leukemia 1 (MLL1) methylates histone H3 on lysine 4 (H3K4) to promote genome accessibility and transcription. Dysregulation or mutation of the KMT2 family have been found in human cancer, exemplified by the initial discovery of KMT2A rearrangements as causes of MLL.