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BMP2K, Active
BMP2K, Active
- 中文名称：
- BMP2K, Active
- 英文名称：
- BMP2K, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73251
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein st ored in 50mM Tris-HCl, pH7.5, 300mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant mouse BMP2K (1-422) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_080708.
BMP2K or Bone morphogenic protein 2 inducible kinase is the human homolog of mouse BMP-2-inducible kinase which plays a key role in skeletal development and patterning. BMP2K is a serine/threonine protein kinase which contains a nuclear localization signal and plays a regulatory role in attenuating the program of osteoblast differentiation. BMP2K gene is strongly correlated with high myopia and may contribute to a genetic risk factor for high degrees of myopic pathogenesis (1). BMP-2 expression is suppressed by an EP4 receptor antagonist and PGE2 produced by COX-2 increases BMP-2 expression via binding the EP4 receptor (2).
