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CLK4, Active
CLK4, Active
- 中文名称：
- CLK4, Active
- 英文名称：
- CLK4, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73370
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human CLK4 (70-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The CLK4 gene accession number is NM_020666.
CLK4 or CDC-like kinase 4 belongs to the CDC2-like protein kinase (CLK) family that can interact with and phosphorylate the serine-and arginine-rich (SR) proteins. The SR proteins are known to play an important role in the formation of spliceosomes and thus may be involved in the regulation of alternative splicing. CLK4 expressed in E Coli phosphorylated myelin basic protein as a substrate as well as autophosphorylating itself but it did not phosphorylate H2B (1).
