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DGKG, Active
DGKG, Active
- 中文名称：
- DGKG, Active
- 英文名称：
- DGKG, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73414
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM sodium phosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.25mM DTT, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant full-length isoform 1 of human Diacylglycerol kinase gamma (DGKG) was expressed by baculovirus in Sf9 insect cells using an N -terminal His tag. The gene accession number is NM_001346.3.
Diacylglycerol kinase gamma (DGKG) is a member of DGK type I subfamily which have EF-hand motifs and two cysteine-rich regions (C1 domain) in the regulatory domain. These enzymes catalyze the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins such as protein kinase C isoforms and RAS guanyl nucleotide-releasing proteins and some transient receptor potential channels (1). DGKG has been associated with malignancies with its role as tumor suppressor in colorectal cancer (2). DGKG is also implicated in regulation of cell cycle regulation (3).
