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DTYMK, Active
DTYMK, Active
- 中文名称：
- DTYMK, Active
- 英文名称：
- DTYMK, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73426
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 300mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human DTYMK (2-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_012145.
DTYMK belongs to a family of thymidylate kinase proteins (1). DTYMK catalyzes phosphorylation of deoxy-TMP to the corresponding phosphate in the presence of ATP and magnesium. This enzyme is essential for cellular DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs (2). Elevated levels of dTMP have been correlated with poor survival in lung adenocarcinomas hence it is a potential anticancer therapeutic target (3).
