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HERC4, Active
HERC4, Active
- 中文名称:
- HERC4, Active
- 英文名称:
- HERC4, Active
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA73595
- 规格:
- 0.02 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant proteins stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Recombinant human HERC4 (642-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The HERC4 gene accession number is NM_015601.
HERC4 or HECT and RLD domain containing E3 ubiquitin protein ligase 4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins. HERC4 is highly expressed in adult and fetal brain and in all specific brain regions examined.