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MAST3, Active
MAST3, Active
- 中文名称：
- MAST3, Active
- 英文名称：
- MAST3, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73736
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, and 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human MAST3 (1-723a.a.) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number for MAST3 is NM_015016.
MAST3 belongs to the microtubule-associated serine/threonine-protein kinase family, which is characterized by containing a serine/threonine kinase domain and a PDZ domain, and is highly expressed in brain (1). MSAT3 suppresses the degradation and promotes phosphorylation of tumor suppressor PTEN via binding to specific PDZ domains (2). MSAT3 is known to modulate the immune functions in inflammatory bowel diseases via regulating NF-kB, cell adhesion and/or migration and production of pro-inflammatory cytokines (3).
