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SHIP2, Active
SHIP2, Active
- 中文名称：
- SHIP2, Active
- 英文名称：
- SHIP2, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73793
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 20mM MOPS, pH7.5, 300mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant full length human SHIP2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_001567.
The SH2-containing inositol-5?-phosphatase 2 (SHIP2) belongs to the family of the mammalian inositol polyphosphate 5-phosphatases that catalyze the dephosphorylation of phosphoinositides and inositol phosphates with a phosphate at 5-position of the inositol ring. In addition to the N-terminal SH2 domains and N-and C-terminal proline-rich regions with consensus sites for SH3 domain interactions, SHIP2 also contains an SAM domain in the C-terminus interacting with the EphA2 receptor and with a PI 3-kinase effector protein regulating both Arf and Rho GTPases, ARAP3.
