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PTPRC (CD45), Active
PTPRC (CD45), Active
- 中文名称:
- PTPRC (CD45), Active
- 英文名称:
- PTPRC (CD45), Active
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA73843
- 规格:
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议:
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- Recombinant protein stored in 20mM MOPS, pH7.5, 300mM NaCl, 10mM glutathione, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Recombinant mouse PTPRC (592-end) was expressed in E Coli cells using an N-terminal GST tag. The gene accession number is NM_001111316.
PTPRC (CD45) contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP (1). This gene is specifically expressed in hematopoietic cells (2). PTPRC has been shown to be an essential regulator of T-and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling (3).