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PRKX, Active
PRKX, Active
- 中文名称：
- PRKX, Active
- 英文名称：
- PRKX, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA73883
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Full-length recombinant human PRKX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_005044.
PRKX is a serine/threonine protein kinase that is closely related to the catalytic subunit of the cAMP-dependent protein kinase. PRKX regulates epithelial morphogenesis during mammalian kidney development and PRKX expression markedly activates migration of cultured renal epithelial cells in the presence of cAMP. Aberrant adult kidney expression of PRKX is found in autosomal dominant polycystic kidney disease (1). PRKX is involved in macrophage and granulocyte maturation. Abnormal recombination between PRKX and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females (2).
