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TYRO3, Active
TYRO3, Active
- 中文名称：
- TYRO3, Active
- 英文名称：
- TYRO3, Active
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA74068
- 规格：
- 0.01 mg|0.05 mg|0.5 mg|2x0.5 mg|3x0.5 mg
- 保存建议：
- Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant human TYRO3 (455-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_006293.
TYRO3 receptor protein tyrosine kinase together with AXL and MER form the AXL/TYRO3 family of receptor tyrosine kinases (1). Members of this family play an essential role in spermatogenesis, immunoregulation, and phagocytosis. In addition to signal transduction, members of this family of receptor tryrosine kinases participate in cell adhesion (2). Gas6, a product of growth arrest-specific gene, activates the kinase activity of all three receptors. TYRO3 is expressed in the brain (where it is involved in the protection of neurons from apoptosis), expressed in lymphoid, vascular and reproductive tissue and in primary and tumor cell lines.
