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SGLT1 Positive Control
SGLT1 Positive Control
- 中文名称：
- SGLT1 Positive Control
- 英文名称：
- SGLT1 Positive Control
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA75986
- 规格：
- 5 Applications|2x5 Applications|3x5 Applications|4x5 Applications|5x5 Applications
- 保存建议：
- Store at -20°C for long term storage
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Western Blot Positive Control in ready to use SDS-sample buffer
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Western Blot Positive Control Sodum/glucose cotransporter 1
Sodium-glucose linked transporters (SGL T) are a family of glucose tranporters that contribute to renal glucose reabsorption. The two most common members of SGL T family are members of the SLC5A gene family: SGL T1 and SGL T2. There are five other members in the human protein family SLC5A, which may also be sodium-glucose transporters (1). SGL Ts utilize secondary active transport to transport glucose along kidney proximal tubules by sodium ion cotransport with a sodium ion to glucose coupling ration of 2:1. A Na+/K+ ATPase pump on the basolateral membrane of the proximal tubules cells utilizes ATP to move 3 Sodium ions outward into the blood, and 2 potassium ions into the cell. The energy from the resulting downhill sodium ion gradient is utilized by SGL Ts to transport glucose across the apical membrane. Since sodium and glucose are transported in the same direction, SGL Ts are classified as symporters. SGL Ts are mainly expressed in intestine and kidney. SGL T and GLUT antibodies have been fully characterized for cross reactivity within the SGL T and GLUT families and also with other cellular proteins. Antibodies against multiple epitopes on the same protein to facilitate studies using interspecies cross reactivity. SGL T western blot positive control (PC-SGL T) is available in read-to-use SOS-PAGE sample buffer. The SGL T positive control appears as a diffuse band of 69-72 and co-migrates with rat jejune.1 sodium-dependent glucose transporter protein on a 10% SOS-PAGE.
