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Human Insulin Like Growth Factor-I Recombinant
Human Insulin Like Growth Factor-I Recombinant
- 中文名称:
- Human Insulin Like Growth Factor-I Recombinant
- 英文名称:
- Human Insulin Like Growth Factor-I Recombinant
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA76064
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.
Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >95%, as determined by SDS-PAGE and HPLC
- 产品形式:
- Recombinant Human IGF1 was lyophilized from a 0.2 um filtered PBS solution, pH 7.4.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Insulin-like growth factor I, also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. Human IGF-I is synthesized as two precursor isoforms with N- and alternate C- terminal propeptides (1). These isoforms are differentially expressed by various tissues (1). The 7.6 kDa mature IGF-I is identical between isoforms and is generated by proteolytic removal of the N- and C- terminal regions. Mature human IGF-I shares 94% and 96% aa sequence identity with mouse and rat IGF-I, respectively (2), and exhibits cross-species activity. It shares 64% aa sequence identity with mature human IGF-II. Circulating IGF-I is produced by hepatocytes, while local IGF-I is produced by many other tissues in which it has paracrine effects.