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Human Stem Cell Factor Recombinant
Human Stem Cell Factor Recombinant
- 中文名称:
- Human Stem Cell Factor Recombinant
- 英文名称:
- Human Stem Cell Factor Recombinant
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA76098
- 规格:
- 0.002 mg|0.01 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- The lyophilized protein is stable for at least 2 years from date of receipt at -20 degree C.
Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
- 货期:
- 6-8周
- 纯度:
- >97%, as determined by SDS-PAGE and HPLC
- 产品形式:
- Recombinant SCF was lyophilized from a 0.2 um filtered solution inPBS pH 7.0.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
SCF is a stromal cell-derived cytokine synthesized by fibroblasts and other cell types. SCF promotes proliferation and early differentiation of cells at the level of multipotential stem cells. It has been suggested that SCF is essential for optimal production of various hematopoietic lineages, mainly because of its ability to prevent apoptosis when it co-stimulates with other cytokines. The receptor for SCF, designated SCFR (CD117), is the oncogene designated as KIT. The biological activities of SCF are synergised considerably by colony stimulating factors GM-CSF and G-CSF, and also by IL7, Epo and some other growth and differentiation factors. In combination with IL7 SCF stimulates the proliferation of pre-B-cells. SCF is also a potent chemoattractant for cells (see also: Chemotaxis), for example, mast cells, expressing the kit receptor. One response to SCF in these cells is a characteristic rearrangement of the actin filaments of the cytoskeleton.