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CpG ODN (2216), TLR9 ligand (Class A)
CpG ODN (2216), TLR9 ligand (Class A)
- 中文名称：
- CpG ODN (2216), TLR9 ligand (Class A)
- 英文名称：
- CpG ODN (2216), TLR9 ligand (Class A)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78391
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Upon receipt, store at -20°C (Stable for up to at least 6 months).
Avoid frequent freeze/thaw cycles.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- 1 mg/ml in entotoxin-free water
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Sequence: 5'-gggggaCGatCGtCGggggg-3' (Class A ODN 2216: Bases are phosphorothioate.) Synthetic oligodeoxynucleotides (ODN) containing unmethylated deoxycytosine-deoxyguanosine (CpG) motif are equivalent to bacterial DNA in the immunostimulatory activity, which can induce innate immunity via Toll-like receptor 9 (TLR9) in mammals. There are three major classes of CpG ODNs, and each ODN class exhibits different stimulatory effects on immune cell activation. Class A ODNs are potent inducers of IFN-alpha that leads to the plasmacytoid dendritc cell (pDC) maturation. Class B ODNs are relatively weak inducers of type I IFNs but strong stimulators of human B cells and monocyte maturation. Class C ODNs combine elements of both Classes A and B ODNs, which can induce IFN-alpha in pDC and activation of B cells.
