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Recombinant Human PD-L1 Fc Fusion Protein (Active)
Recombinant Human PD-L1 Fc Fusion Protein (Active)
- 中文名称:
- Recombinant Human PD-L1 Fc Fusion Protein (Active)
- 英文名称:
- Recombinant Human PD-L1 Fc Fusion Protein (Active)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA78593
- 规格:
- 0.025 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议:
- Store it under sterile conditions at -4 degree C. It is recommended that the protein be aliquoted for optimal storage.
- 货期:
- 6-8周
- 纯度:
- 99% Purity SDS -PAGE and HPLC.
- 产品形式:
- Lyophilized sterile PBS, 5% trehalose and 0.01% tween 80 are added as protectant before lyophilization.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases.