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Recombinant Human Leukocyte Elastase Inhibitor/Serpin B1/SERPINB1 (C-6His)
Recombinant Human Leukocyte Elastase Inhibitor/Serpin B1/SERPINB1 (C-6His)
- 中文名称：
- Recombinant Human Leukocyte Elastase Inhibitor/Serpin B1/SERPINB1 (C-6His)
- 英文名称：
- Recombinant Human Leukocyte Elastase Inhibitor/Serpin B1/SERPINB1 (C-6His)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78607
- 规格：
- 0.01 mg|0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg
- 保存建议：
- Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
- 货期：
- 6-8周
- 纯度：
- N/A
- 产品形式：
- Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant Human Serpin B1/Leukocyte elastase inhibitor is produced by our Mammalian expression system and the target gene encoding Met1-Pro379 is expressed with a 6His tag at the C-terminus. SERPINB1 is a member of the serpin family and Ov-serpin subfamily. As protease inhibitors, serpins have an array of functions including regulating blood coagulation, fibrinolysis, the complement pathway, angiogenesis, inflammation, tumor suppression, extracellular matrix remodeling, and cell motility. SERPINB1 regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Reactive bond 1 of SerpinB1 is specific for reaction with chymotrypsin-like protease such as cathepsin G, chymotrypsin or chymase. Reactive bond 2 of SerpinB1 is specific for reaction with elastase-like protease such as neutrophyl elastase, proteinase-3, pancreatic elastase or PSA. In addition, SERPINB1 also functions as a potent intracellular inhibitor of granzyme H.
