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Human Wnt-5a
Human Wnt-5a
- 中文名称：
- Human Wnt-5a
- 英文名称：
- Human Wnt-5a
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79315
- 规格：
- 0.025 mg|2x0.025 mg|3x0.025 mg|5x0.025 mg|4x0.025 mg
- 保存建议：
- Store at 2-8 degree C for up to 1 week or prepare for extended storage
After initial reconstitution, prepare and store working aliquots at -20 degree to -80 degree C.
Avoid repeated freeze/thaw cycles
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE & Coomassie stain
- 产品形式：
- Sterile filtered protein solution was lyophilized from 50 mM acetic acid, free stabilizers and preservatives
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Wnt-5a is one of the most highly investigated non-canonical Wnts and has been implicated in almost all aspects of non-canonical Wnt signalling. In terms of cancer development, Wnt-5a has, until recently, lived in the shadow of its better-characterised relatives. This was largely because of its apparent inability to transform cells or signal through the canonical beta-catenin pathway that is so important in cancer, particularly colorectal cancer. Recent work in a wide range of human tumours has pointed to a critical role for Wnt-5a in malignant progression, but there is conflicting evidence whether Wnt-5a has a tumour-promoting or -suppressing role. Emerging evidence suggests that the functions of Wnt-5a can be drastically altered depending on the availability of key receptors. Hence, the presence or absence of these receptors may go some way to explain the conflicting role of Wnt-5a in different cancers.
