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Rabbit anti-Mouse IgG Fc fragment polyclonal Antibody, HRP conjugated
Rabbit anti-Mouse IgG Fc fragment polyclonal Antibody, HRP conjugated
- 中文名称：
- Rabbit anti-Mouse IgG Fc fragment polyclonal Antibody, HRP conjugated
- 英文名称：
- Rabbit anti-Mouse IgG Fc fragment polyclonal Antibody, HRP conjugated
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA81452
- 规格：
- 0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg|5x0.5 mg
- 保存建议：
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
- 货期：
- 6-8周
- 纯度：
- Caprylic Acid Ammonium Sulfate Precipitation Purified
- 产品形式：
- Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2-4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and alpha-2,6 linked sialic acid residues. The other part of an antibody, called the Fab region, contains variable sections that define the specific target that the antibody can bind. By contrast, the Fc region of all antibodies in a class are the same for each species; they are constant rather than variable. The Fc region is, therefore, sometimes incorrectly termed the "fragment constant region".
