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Anti-TMEM119 Antibody FL550 Conjugate
Anti-TMEM119 Antibody FL550 Conjugate
- 中文名称：
- Anti-TMEM119 Antibody FL550 Conjugate
- 英文名称：
- Anti-TMEM119 Antibody FL550 Conjugate
- 品牌：
- NeuroMab
- 品牌介绍：
- NeuroMab是美国国立卫生研究院神经单抗研究所成立于2004年，旨在生产可用于神经学研究的小鼠单克隆抗体。这些抗体广泛应用于动物脑组织样本检测，包括免疫印迹、免疫组化等。引用NeuroMab的产品发表的文献，已超过：3300篇。
- 货号：
- 75-512-FL550
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- TMEM119, is a plasma membrane protein first identified because of its role in the differentiation of osteoblasts (Kanamoto et al., 2009). However TMEM119 is also known to be a specific marker of microglia, the tissue-resident macrophages of brain and spinal cord (Bennett et al., 2016). Unlike other microglia markers, TMEM119 expression readily distinguishes resident microglia from blood-derived macrophages, making it a highly specific microglia marker. In healthy brain microglia are the resident immune cells where they act to neutralize pathogens, clear dead and dying cells, and prune synaptic connections. However, in neurodegenerative disease microglia can actually promote neuronal degeneration through reduced phagocytic clearance and increased pro-inflammatory effects. Our anti-TMEM119 antibody is a highly specific microglial marker for mouse TMEM119 and works by western blot and immunocytochemistry.
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 反应种属：
- Mouse
- 应用：
- IHC, ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
- 说明书：
Our Anti-TMEM119, OBIF mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L128/43. It detects mouse TMEM119, OBIF, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
