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Anti-Tyrosine Hydroxylase Antibody (Ascites)
Anti-Tyrosine Hydroxylase Antibody (Ascites)
- 中文名称：
- Anti-Tyrosine Hydroxylase Antibody (Ascites)
- 英文名称：
- Anti-Tyrosine Hydroxylase Antibody (Ascites)
- 品牌：
- Antibodies Inc
- 品牌介绍：
- Antibodies Inc.成立于1962年， 在神经科学领域备受推崇，拥有针对关键神经科学靶点的一流小鼠单克隆抗体。最初专注于二抗和免疫测定，在2005年，与加州大学戴维斯分校和美国国立卫生研究院合作，成为高度验证的NeuroMab系列小鼠单克隆抗体的商业供应商。这些高品质的抗体经过全部测试，数十种已进行基因敲除验证，并提供四种不同荧光标记物的抗体。我们的定制抗体服务提供量身定制的解决方案，包括单克隆和多克隆选项，以及生产、共轭和免疫测定服务。所有这些工作都在位于加利福尼亚州戴维斯的ISO-13485认证设施中完成。
- 货号：
- 76-700
- 规格：
- 100 µL
- 保存建议：
- 分装后于 ≤ -20°C 长期储存；短期储存可保存于 2–8°C。为最大限度回收产品，请在打开瓶盖前先离心试剂瓶。
- 背景资料：
- TH is the rate-limiting enzyme in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine and is responsible for converting L-tyrosine to L-dopa. Synthesis of catecholamines is regulated by the interaction of TH with its’ cofactor, tetrahydrobiopterin (BH4) and the substrates L-tyrosine and molecular oxygen. In humans four TH mRNA splice variants (hTH1-hTH4) have been isolated while subprimate species rely on a single form of TH. It is known that the hTH1-hTH4 variants are identical in their catalytic domain but differ in their N-terminal regulatory domains. Importantly, LNC1 reacts with the catalytic domain of TH and thus with all four isoforms of human TH. The role of TH in the synthesis of catecholamine neurotransmitters suggests a connection between the enzyme and a number of neuropathogenic diseases characterized by irregular catecholamine levels, such as Parkinson's disease, schizophrenia, and dystonia, as well as a variety of cardiovascular diseases.
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 反应种属：
- Chicken, Frog, Human, Lizard, Monkey, Mouse, Rat, Vole, and Zebrafish
- 应用：
- WB, IHC, ICC, IP, ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
免疫原物种：Human
克隆性：Monoclonal
克隆号：LNC1
浓度：Ascites fluid
分子量：59-63 kDa
- 说明书：
Our Anti-Tyrosine Hydroxylase (TH) mouse monoclonal primary antibody from Antibodies Incorporated is produced in-house from hybridoma clone LNC1. It detects chicken, frog, human, lizard, monkey, mouse, rat, vole, and zebrafish Tyrosine Hydroxylase (TH), and is ascites fluid. It is great for use in WB, IHC, ICC, IP, ELISA.
