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Anti-Tyrosine Hydroxylase Antibody (Purified) FL490 Conjugate
Anti-Tyrosine Hydroxylase Antibody (Purified) FL490 Conjugate
- 中文名称：
- Anti-Tyrosine Hydroxylase Antibody (Purified) FL490 Conjugate
- 英文名称：
- Anti-Tyrosine Hydroxylase Antibody (Purified) FL490 Conjugate
- 品牌：
- NeuroMab
- 品牌介绍：
- NeuroMab是美国国立卫生研究院神经单抗研究所成立于2004年，旨在生产可用于神经学研究的小鼠单克隆抗体。这些抗体广泛应用于动物脑组织样本检测，包括免疫印迹、免疫组化等。引用NeuroMab的产品发表的文献，已超过：3300篇。
- 货号：
- 77-700-FL490
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- TH is the rate-limiting enzyme in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine and is responsible for converting L-tyrosine to L-dopa. Synthesis of catecholamines is regulated by the interaction of TH with its’ cofactor, tetrahydrobiopterin (BH4) and the substrates L-tyrosine and molecular oxygen. In humans four TH mRNA splice variants (hTH1-hTH4) have been isolated while subprimate species rely on a single form of TH. It is known that the hTH1-hTH4 variants are identical in their catalytic domain but differ in their N-terminal regulatory domains. Importantly, LNC1 reacts with the catalytic domain of TH and thus with all four isoforms of human TH. The role of TH in the synthesis of catecholamine neurotransmitters suggests a connection between the enzyme and a number of neuropathogenic diseases characterized by irregular catecholamine levels, such as Parkinson's disease, schizophrenia, and dystonia, as well as a variety of cardiovascular diseases.
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 反应种属：
- Chicken, Frog, Human, Lizard, Monkey, Mouse, Rat, Vole, and Zebrafish
- 应用：
- IHC, ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
Our Anti-Tyrosine Hydroxylase (TH) mouse monoclonal primary antibody from Antibodies Incorporated is produced in-house from hybridoma clone LNC1. It detects chicken, frog, human, lizard, monkey, mouse, rat, vole, and zebrafish Tyrosine Hydroxylase (TH), and is purified by Protein A chromatography. It is great for use in IHC, ICC.
