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Anti-mOPN4 (Melanopsin) Antibody
Anti-mOPN4 (Melanopsin) Antibody
- 中文名称：
- Anti-mOPN4 (Melanopsin) Antibody
- 英文名称：
- Anti-mOPN4 (Melanopsin) Antibody
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- mOPN4-0100
- 规格：
- 500 µL
- 保存建议：
- Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
- 背景资料：
- The melanopsin protein (mOPN4), encoded by the OPN4 gene, is a photopigment found in specialized retinal ganglion cells (Hughes et al. 2016). mOPN4 plays a crucial role in non-image-forming visual processes, including the regulation of circadian rhythms, pupillary light reflex, and mood modulation (Pan et al. 2023 and Roecklein et al. 2009). Unlike rod and cone photoreceptors responsible for traditional image formation, mOPN4-expressing cells respond to light intensity and are key to synchronizing the body’s internal clock with environmental light-dark cycles. Disruptions in mOPN4 signaling are linked to various disorders, such as seasonal affective disorder, sleep disturbances, and even metabolic conditions. Research in recent years has revealed OPN4’s role in the photosensitive system of human skin (Sua-Cespedes et al 2023, Kusumoto et al. 2020), and it is even implicated in cutaneous melanoma (de Assis et al. 2022).
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Mouse
- 应用：
- ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:200 µg/mL
推荐稀释比（WB）:N/A
推荐稀释比（WB Brain）:N/A
推荐稀释比（IHC）:N/A
推荐稀释比（ICC）:1:1000-1:10,000
- 说明书：
Our Anti-Mouse Opsin 4/Melanopsin chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects mOPN4, and is affinity-purified IgY. It is great for use in ICC.
