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Anti-S100B Antibody Trial Size
Anti-S100B Antibody Trial Size
- 中文名称：
- Anti-S100B Antibody Trial Size
- 英文名称：
- Anti-S100B Antibody Trial Size
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- S100B-0020
- 规格：
- 100 µL
- 保存建议：
- Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
- 背景资料：
- S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. By contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells. S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells. This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metastasis.S100 protein is atype of low molecular weight protein found in vertebrates characterized by twocalcium binding sites of the helix-loop-helix ("EF-hand type")conformation. There are at least 21 different types of S100 proteins. The nameis derived from the fact that the protein is 100% soluble in ammonium sulfateat neutral pH. Most S100 proteins are homodimeric, consisting of two identicalpolypeptides held together by non-covalent bonds. S100A is composed of an alphaand a beta chain whereas S100B is composed of two beta chains. Although S100proteins are structurally similar to calmodulin, they differ in that they arecell-specific, expressed in particular cells at different levels depending onenvironmental factors. By contrast, calmodulin is a ubiquitous and universalintracellular Ca++ receptor widely expressed in many cells. S-100 is normallypresent in cells derived from the neural crest (Schwann cells, melanocytes, andglia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages,Langerhans cells, dendritic cells, and keratinocytes. It may be present in somebreast epithelial cells. This antibody stains schwannoma, ependymomas,astrogliomas, almost all benign and malignant melanoma and their metastasis.S100 protein is a type of low molecular weightprotein found in vertebrates characterized by two calcium binding sites of thehelix-loop-helix ("EF-hand type") conformation. There are at least 21different types of S100 proteins. The name is derived from the fact that theprotein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteinsare homodimeric, consisting of two identical polypeptides held together bynon-covalent bonds. S100A is composed of an alpha and a beta chain whereasS100B is composed of two beta chains. Although S100 proteins are structurallysimilar to calmodulin, they differ in that they are cell-specific, expressed inparticular cells at different levels depending on environmental factors. Bycontrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptorwidely expressed in many cells. S-100 is normally present in cells derived fromthe neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte,adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendriticcells, and keratinocytes. It may be present in some breast epithelial cells.This antibody stains schwannoma, ependymomas, astrogliomas, almost all benignand malignant melanoma and their metastasis.S100 protein is a type of low molecular weightprotein found in vertebrates characterized by two calcium binding sites of thehelix-loop-helix ("EF-hand type") conformation. There are at least 21different types of S100 proteins. The name is derived from the fact that theprotein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteinsare homodimeric, consisting of two identical polypeptides held together bynon-covalent bonds. S100A is composed of an alpha and a beta chain whereasS100B is composed of two beta chains. Although S100 proteins are structurallysimilar to calmodulin, they differ in that they are cell-specific, expressed inparticular cells at different levels depending on environmental factors. Bycontrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptorwidely expressed in many cells. S-100 is normally present in cells derived fromthe neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte,adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendriticcells, and keratinocytes. It may be present in some breast epithelial cells.This antibody stains schwannoma, ependymomas, astrogliomas, almost all benignand malignant melanoma and their metastasis.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Human, Mouse, and Rat
- 应用：
- ICC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.2 mg/ml
推荐稀释比（WB Brain）:1:500-1:1000
推荐稀释比（IHC）:1:500-1:1000
推荐稀释比（ICC）:1:100-1:500
- 说明书：
Our Anti-S100B chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat S100B, and is affinity-purified IgY. It is great for use in ICC, WB.
