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Anti-SQSTM1 Antibody
Anti-SQSTM1 Antibody
- 中文名称：
- Anti-SQSTM1 Antibody
- 英文名称：
- Anti-SQSTM1 Antibody
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- SQSTM1-0100
- 规格：
- 500 µL
- 保存建议：
- Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
- 背景资料：
- Sequestosome 1 (SQSTM1), also known as p62, is a multifunctional adaptor protein involved in autophagy, cell signaling, and protein degradation. It plays a key role in selectively targeting ubiquitinated proteins for degradation via the autophagy-lysosome pathway and is also involved in NF-κB signaling, oxidative stress responses, and bone metabolism. Mutations in SQSTM1 are strongly associated with Paget’s disease of bone and have been implicated in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and certain cancers. Due to its role in cellular homeostasis, SQSTM1 remains a significant focus in research on autophagy-related diseases and targeted therapies.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Human, Mouse, and Rat
- 应用：
- ICC, IHC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:200 µg/mL
推荐稀释比（WB）:1:5000 - 1:10000
推荐稀释比（IHC）:1:100 - 1:200
推荐稀释比（ICC）:1:100 - 1:200
- 说明书：
Our Anti-SQSTM1 chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat SQSTM1, and is affinity-purified IgY. It is great for use in ICC, IHC, WB.
