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Anti-TMEM119 (L128/43) Recombinant Chicken Chimeric mAb FL650 Conjugate
Anti-TMEM119 (L128/43) Recombinant Chicken Chimeric mAb FL650 Conjugate
- 中文名称：
- Anti-TMEM119 (L128/43) Recombinant Chicken Chimeric mAb FL650 Conjugate
- 英文名称：
- Anti-TMEM119 (L128/43) Recombinant Chicken Chimeric mAb FL650 Conjugate
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- 78-512-FL650
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- TMEM119, is a plasma membrane protein first identified because of its role in the differentiation of osteoblasts (Kanamoto et al., 2009). However TMEM119 is also known to be a specific marker of microglia, the tissue-resident macrophages of brain and spinal cord (Bennett et al., 2016). Unlike other microglia markers, TMEM119 expression readily distinguishes resident microglia from blood-derived macrophages, making it a highly specific microglia marker. In healthy brain microglia are the resident immune cells where they act to neutralize pathogens, clear dead and dying cells, and prune synaptic connections. However, in neurodegenerative disease microglia can actually promote neuronal degeneration through reduced phagocytic clearance and increased pro-inflammatory effects. Our anti-TMEM119 antibody is a highly specific microglial marker for mouse TMEM119 and works by western blot and immunocytochemistry.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Mouse
- 应用：
- ICC, IHC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
Our chicken Anti-TMEM119, OBIF recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone L128/43. It detects mouse TMEM119, OBIF, and is purified by affinity chromatography. It is great for use in ICC, IHC, WB.
