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Anti-Cortactin (4F11-G5-F10) Recombinant Chicken Chimeric mAb
Anti-Cortactin (4F11-G5-F10) Recombinant Chicken Chimeric mAb
- 中文名称：
- Anti-Cortactin (4F11-G5-F10) Recombinant Chicken Chimeric mAb
- 英文名称：
- Anti-Cortactin (4F11-G5-F10) Recombinant Chicken Chimeric mAb
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- 78-601
- 规格：
- 100 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- Cortactin is an ~80–85 kDa actin-binding protein that orchestrates cytoskeletal remodeling and signal integration. It contains an N-terminal repeat domain that associates with filamentous actin, followed by a helical segment, a proline-rich region with multiple signaling motifs, and a C-terminal SH3 domain. Through interactions with the Arp2/3 complex and other regulators, cortactin promotes actin branching, lamellipodia formation, and endocytic trafficking. Tyrosine phosphorylation by Src family kinases inhibits its actin crosslinking activity, linking receptor-mediated signals to cytoskeletal rearrangements. Aberrant cortactin activity has been implicated in tumor cell invasion, metastasis, and vascular permeability disorders, highlighting its importance in both normal cellular dynamics and disease progression.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Bovine, Chicken, Hamster, Human, Mouse, and Rat
- 应用：
- WB, IHC, ICC, IP
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:1 mg/mL
推荐稀释比（WB）:1:1000-1:3000
推荐稀释比（IHC）:1:100-1:500
推荐稀释比（ICC）:1:100-1:500
- 说明书：
Our Anti-Cortactin chicken recombinant primary antibody from Aves Labs is produced in-house from hybridoma clone 4F11-G5-F10. It detects human, mouse, rat, hamster, bovine, chicken, and avian Cortactin, and is purified by affinity chromatography. It is great for use in WB, IHC, ICC, IP.
