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Anti-Rab 9 (clone 9) Recombinant Chicken Chimeric mAb FL490 Conjugate
Anti-Rab 9 (clone 9) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 中文名称：
- Anti-Rab 9 (clone 9) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 英文名称：
- Anti-Rab 9 (clone 9) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- 78-604-FL490
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- Rab9 is a small GTP-binding protein of the Rab family that regulates late endosomal trafficking. It is primarily involved in the transport of mannose-6-phosphate receptor-containing vesicles from late endosomes back to the trans-Golgi network, a pathway critical for proper lysosomal enzyme sorting and recycling. Like other Rab proteins, Rab9 functions as a molecular switch, cycling between an active GTP-bound state and an inactive GDP-bound state, with its activity controlled by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). Rab9-mediated trafficking ensures the steady-state distribution of cation-dependent and cation-independent mannose-6-phosphate receptors and contributes to lysosomal homeostasis. Dysregulation of Rab9 function has been linked to impaired lysosomal degradation, altered receptor recycling, and has emerging associations with cancer progression, viral infection, and lysosomal storage disorders.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Bovine, Canine, Hamster, Human, Mouse, Non-Human Primate, and Rat
- 应用：
- IHC, ICC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
推荐稀释比（IHC）:1:50-1:200
推荐稀释比（ICC）:1:50-1:200
Our Anti-Rab 9 chicken recombinant primary antibody from Aves Labs is produced in-house from hybridoma clone Clone 9. It detects human, mouse, rat, dog, bovine, hamster, and non-human primate Rab 9, and is purified by affinity chromatography. It is great for use in IHC, ICC.
