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Anti-Tyrosine Hydroxylase (LNC1) Recombinant Chicken Chimeric mAb FL490 Conjugate
Anti-Tyrosine Hydroxylase (LNC1) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 中文名称：
- Anti-Tyrosine Hydroxylase (LNC1) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 英文名称：
- Anti-Tyrosine Hydroxylase (LNC1) Recombinant Chicken Chimeric mAb FL490 Conjugate
- 品牌：
- Aves Labs
- 品牌介绍：
- Aves Labs自1995年以来一直引领着高度验证的鸡抗体开发行业，并提供以神经科学为重点的产品目录。鸡与哺乳动物在进化上有所不同，它们产生IgY抗体，可以更有选择性地靶向高度保守的哺乳动物蛋白质。鸡抗体也是当今非常热门的多重检测应用的首选。Aves Labs开创了寻找蛋白质中非常高免疫原性序列的新算法，并利用这一专业知识生产性能无与伦比的抗体。在位于加利福尼亚州戴维斯的ISO-13485认证设施中，不断开发新型抗体，并提供定制抗体服务。
- 货号：
- 78-700-FL490
- 规格：
- 200 µL
- 保存建议：
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- 背景资料：
- TH is the rate-limiting enzyme in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine and is responsible for converting L-tyrosine to L-dopa. Synthesis of catecholamines is regulated by the interaction of TH with its’ cofactor, tetrahydrobiopterin (BH4) and the substrates L-tyrosine and molecular oxygen. In humans four TH mRNA splice variants (hTH1-hTH4) have been isolated while subprimate species rely on a single form of TH. It is known that the hTH1-hTH4 variants are identical in their catalytic domain but differ in their N-terminal regulatory domains. Importantly, LNC1 reacts with the catalytic domain of TH and thus with all four isoforms of human TH. The role of TH in the synthesis of catecholamine neurotransmitters suggests a connection between the enzyme and a number of neuropathogenic diseases characterized by irregular catecholamine levels, such as Parkinson's disease, schizophrenia, and dystonia, as well as a variety of cardiovascular diseases.
- 货期：
- 4-6周
- 来源宿主：
- Chicken
- 反应种属：
- Chicken, Frog, Human, Lizard, Monkey, Mouse, Rat, Vole, and Zebrafish
- 应用：
- ICC, IHC
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
浓度:0.5 mg/mL
Our chicken Anti-Tyrosine Hydroxylase (TH) recombinant monoclonal antibody is a chimeric antibody derived from clone LNC1. It detects chicken, frog, human, lizard, monkey, mouse, rat, vole, and zebrafish Tyrosine Hydroxylase (TH) and is purified by affinity chromatography. It works in ICC, IHC.
