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Anti-Internexin alpha (Alpha-Inx) Antibody
Anti-Internexin alpha (Alpha-Inx) Antibody
- 中文名称:
- Anti-Internexin alpha (Alpha-Inx) Antibody
- 英文名称:
- Anti-Internexin alpha (Alpha-Inx) Antibody
- 品牌:
- Biosensis
- 货号:
- M-1378-250
- 规格:
- 250 µg
- 保存建议:
- Spin vial briefly before opening. Reconstitute with 250 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- 背景资料:
- Neurofilaments can be defined as the intermediate or 10 nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
- 货期:
- 4-6周
- 来源宿主:
- Mouse
- 应用:
- ICC, IHC-Frozen, IHC-Paraffin-embedded, WB
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
Our Anti-Internexin alpha (Alpha-Inx) mouse monoclonal primary antibody detects cat, human, mouse, other mammals, and rat Internexin alpha (Alpha-Inx), and is igg. It is validated for use in ICC, IHC-Frozen, IHC-Paraffin-embedded, WB.