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Anti-Alpha-Synuclein Antibody
Anti-Alpha-Synuclein Antibody
- 中文名称：
- Anti-Alpha-Synuclein Antibody
- 英文名称：
- Anti-Alpha-Synuclein Antibody
- 品牌：
- Biosensis
- 货号：
- M-1402-100
- 规格：
- 100 µL
- 保存建议：
- Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, divide into single use aliquots and store at -20-80°C for a higher stability. Avoid freeze-thaw cycles.
- 背景资料：
- Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. FUNCTION: May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase 3 activation. TISSUE SPECIFICITY: Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.SUBUNIT: Soluble monomer which can form filamentous aggregates. Interacts with UCHL1. Interacts with phospholipase D and histones. SUBCELLULAR LOCATION: Cytoplasm. Membrane. Nucleus. Note=Membrane-bound in dopaminergic neurons. Also found in the nucleus. ALTERNATIVE PRODUCTS: 3 named isoforms produced by alternative splicing. Additional isoforms seem to exist.
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 应用：
- ICC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Alpha-synuclein mouse monoclonal primary antibody detects bovine, chicken, horse, human, mouse, other mammals (predicted), pig, and rat Alpha-synuclein , and is igg. It is validated for use in ICC, WB.
