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Anti-Brain-derived neurotrophic factor (BDNF) Antibody
Anti-Brain-derived neurotrophic factor (BDNF) Antibody
- 中文名称：
- Anti-Brain-derived neurotrophic factor (BDNF) Antibody
- 英文名称：
- Anti-Brain-derived neurotrophic factor (BDNF) Antibody
- 品牌：
- Biosensis
- 货号：
- M-1736-50
- 规格：
- 50 µg
- 保存建议：
- Spin vial briefly before opening. Reconstitute with 50 µL sterile-filtered, ultrapure water to obtain a concentration of 1 mg/mL. Centrifuge to remove any insoluble material. Store lyophilized antibody at -20°C to -80°C protected from moisture. After reconstitution divide antibody into useful aliquots and keep aliquots at -20°C to -80°C for a higher stability. Working aliquots can be kept at 2-8°C for up to 1 month. Avoid repetitive freeze/thaw cycles.
- 背景资料：
- BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.
- 货期：
- 4-6周
- 来源宿主：
- Mouse
- 应用：
- ELISA, ICC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Brain-derived neurotrophic factor (BDNF) mouse monoclonal primary antibody detects human, mouse, other mammals (predicted), and rat Brain-derived neurotrophic factor (BDNF), and is igg. It is validated for use in ELISA, ICC, WB.
