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Anti-NGFR/p75 neurotrophin receptor (p75NTR) Antibody
Anti-NGFR/p75 neurotrophin receptor (p75NTR) Antibody
- 中文名称：
- Anti-NGFR/p75 neurotrophin receptor (p75NTR) Antibody
- 英文名称：
- Anti-NGFR/p75 neurotrophin receptor (p75NTR) Antibody
- 品牌：
- Biosensis
- 货号：
- R-089-100
- 规格：
- 100 µL
- 保存建议：
- Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- 背景资料：
- FUNCTION: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. DOMAIN: Death domain is responsible for interaction with RANBP9. PTM: N- and O-glycosylated. PTM: O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. PTM: Phosphorylated on serine residues. SIMILARITY: Contains 1 death domain. SIMILARITY: Contains 4 TNFR-Cys repeats.
- 货期：
- 4-6周
- 来源宿主：
- Rabbit
- 应用：
- ICC, IHC-Frozen
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-NGFR/p75 neurotrophin receptor (p75NTR) rabbit polyclonal primary antibody detects human and rat NGFR/p75 neurotrophin receptor (p75NTR), and is whole serum. It is validated for use in ICC, IHC-Frozen.
