
-
Anti-Superoxide dismutase 1 (SOD1) Antibody
Anti-Superoxide dismutase 1 (SOD1) Antibody
- 中文名称:
- Anti-Superoxide dismutase 1 (SOD1) Antibody
- 英文名称:
- Anti-Superoxide dismutase 1 (SOD1) Antibody
- 品牌:
- Biosensis
- 货号:
- R-125-100
- 规格:
- 100 µL
- 保存建议:
- Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- 背景资料:
- FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
- 货期:
- 4-6周
- 来源宿主:
- Rabbit
- 应用:
- WB
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
Our Anti-Superoxide dismutase 1 (SOD1) rabbit polyclonal primary antibody detects human Superoxide dismutase 1 (SOD1), and is whole serum. It is validated for use in WB.