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Anti-Autophagy protein 5 (ATG5) Antibody
Anti-Autophagy protein 5 (ATG5) Antibody
- 中文名称：
- Anti-Autophagy protein 5 (ATG5) Antibody
- 英文名称：
- Anti-Autophagy protein 5 (ATG5) Antibody
- 品牌：
- Biosensis
- 货号：
- R-138-500
- 规格：
- 500 µg
- 保存建议：
- Spin vial briefly before opening. Reconstitute with 500 µL of sterile-filtered, ultra pure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- 背景资料：
- FUNCTION: Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. FUNCTION: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. SUBCELLULAR LOCATION: Cytoplasm. Colocalizes with nonmuscle actin. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells. INDUCTION: By apoptotic stimuli. PTM: Conjugated to ATG12; which is essential for autophagy, but is not required for association with isolation membrane. SIMILARITY: Belongs to the ATG5 family.
- 货期：
- 4-6周
- 来源宿主：
- Rabbit
- 应用：
- IHC-Frozen, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Autophagy protein 5 (ATG5) rabbit polyclonal primary antibody detects human Autophagy protein 5 (ATG5), and is igg. It is validated for use in IHC-Frozen, WB.
