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Anti-Autophagy-related protein 3 (ATG3) Antibody
Anti-Autophagy-related protein 3 (ATG3) Antibody
- 中文名称:
- Anti-Autophagy-related protein 3 (ATG3) Antibody
- 英文名称:
- Anti-Autophagy-related protein 3 (ATG3) Antibody
- 品牌:
- Biosensis
- 货号:
- R-159-100
- 规格:
- 100 µL
- 保存建议:
- Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- 背景资料:
- FUNCTION: GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3 (E2-like enzyme). Preferred substrate is MAP1LC3A. Formation of the GABARAPL1-PE conjugate is essential for autophagy. SUBUNIT: Interacts with ATG7 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5. SUBCELLULAR LOCATION: Cytoplasm. ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing. TISSUE SPECIFICITY: Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta. SIMILARITY: Belongs to the ATG3 family.
- 货期:
- 4-6周
- 来源宿主:
- Rabbit
- 应用:
- IHC-Frozen, IHC-Paraffin-embedded, WB
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
Our Anti-Autophagy-related protein 3 (ATG3) rabbit polyclonal primary antibody detects human, mouse, and rat Autophagy-related protein 3 (ATG3), and is whole serum. It is validated for use in IHC-Frozen, IHC-Paraffin-embedded, WB.