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Anti-Growth Associated Protein 43 (GAP-43) Antibody
Anti-Growth Associated Protein 43 (GAP-43) Antibody
- 中文名称：
- Anti-Growth Associated Protein 43 (GAP-43) Antibody
- 英文名称：
- Anti-Growth Associated Protein 43 (GAP-43) Antibody
- 品牌：
- Biosensis
- 货号：
- R-1651-100
- 规格：
- 100 µg
- 保存建议：
- Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized, unopened vial at 2-8°C or lower. After reconstitution, prepare aliquots and store at -20°C to -80°C for a higher stability. Avoid freeze-thaw cycles.
- 背景资料：
- GAP43 is very abundant protein which is found concentrated in neurons. One group discovered it as one of three proteins which becomes unregulated during the regeneration of the toad optic nerve (1). Three GAPs (Growth associated proteins) were discovered, and the number 43 comes from the apparent SDS-PAGE molecular weight of the one named GAP43. The HGNC name for this protein is, not surprisingly, GAP43. Later work showed that GAP43 does not run on SDS-PAGE in a fashion which accurately reflects its molecular weight, and that GAP43 proteins from different species may run at different apparent molecular weights. Partly due to these features GAP43 were independently discovered by several different groups and therefore has several alternate names, such as protein F1, pp46, neuromodulin, neural phosphoprotein B-50 and calmodulin-binding protein P-57. In each case the number reflects the apparent SDS-PAGE molecular weight, and underlines the unusual properties of this molecule. Mammalian GAP43 proteins contains only 226-243 amino acids, and so the real molecular weight is 23.61-25.14 kDa. GAP43 has been extensively studied and is known to be a major protein kinase C substrate and to bind calmodulin avidly. GAP43 is anchored to the plasma membrane by palmitoylation modifications.
- 货期：
- 4-6周
- 来源宿主：
- Rabbit
- 应用：
- ICC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Growth Associated Protein 43 (GAP-43) rabbit polyclonal primary antibody detects bovine, human, mouse, and rat Growth Associated Protein 43 (GAP-43), and is affinity-purified. It is validated for use in ICC, WB.
