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Anti-Adenylate cyclase type III (ACIII) Antibody
Anti-Adenylate cyclase type III (ACIII) Antibody
- 中文名称：
- Anti-Adenylate cyclase type III (ACIII) Antibody
- 英文名称：
- Anti-Adenylate cyclase type III (ACIII) Antibody
- 品牌：
- Biosensis
- 货号：
- R-1687-100
- 规格：
- 100 µg
- 保存建议：
- Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized, unopened vial at 2-8°C or lower. After reconstitution, prepare aliquots and store at -20°C to -80°C for a higher stability. Avoid freeze-thaw cycles.
- 背景资料：
- Adenylate cyclases are enzymes which interact with and are activated by the GTP bound alpha subunits of trimeric G-proteins. Activated adenylate cyclases are responsible for the production of the important "second messenger" signalling molecule cyclic-AMP, which is generated from ATP. The type III adenylate cyclase enzyme is localized in the membranes surrounding the cilia in neurons, and our antibody is an excellent marker of neuronal cilia in the brain and in cells in tissue culture. Adenylate cyclase type III is a large complex molecule of, in the human, 1145 amino acids with a deduced molecular weight of 129 kDa. The protein may be variably glycosylated, so that on SDS-PAGE and western blots it runs as a diffuse band of about 160 kDa in cortex and about 200 kDa in olfactory epithelium. The molecule has a complex structure, with 12 transmembrane domains and two cyclase domains. Each cyclase domain is immediately C-terminal to 6 transmembrane segments, but only the second, C-terminal cyclase is believed to be catalytically active.
- 货期：
- 4-6周
- 来源宿主：
- Rabbit
- 应用：
- ICC, IHC, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Adenylate cyclase type III (ACIII) rabbit polyclonal primary antibody detects human (predicted), mouse, other mammals (predicted), and rat Adenylate cyclase type III (ACIII), and is affinity-purified. It is validated for use in ICC, IHC, WB.
