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Anti-Ciliary neurotrophic factor (CNTF) Antibody
Anti-Ciliary neurotrophic factor (CNTF) Antibody
- 中文名称：
- Anti-Ciliary neurotrophic factor (CNTF) Antibody
- 英文名称：
- Anti-Ciliary neurotrophic factor (CNTF) Antibody
- 品牌：
- Biosensis
- 货号：
- S-025-100
- 规格：
- 100 µL
- 保存建议：
- Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for an additional stability.
- 背景资料：
- CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.
- 货期：
- 4-6周
- 来源宿主：
- Sheep
- 应用：
- ELISA, IHC-Frozen, WB
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
Our Anti-Ciliary neurotrophic factor (CNTF) sheep polyclonal primary antibody detects human, mouse, and rat Ciliary neurotrophic factor (CNTF), and is whole serum. It is validated for use in ELISA, IHC-Frozen, WB.
