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Human NGFR/p75ECD Rapid ELISA Assay
Human NGFR/p75ECD Rapid ELISA Assay
- 中文名称：
- Human NGFR/p75ECD Rapid ELISA Assay
- 英文名称：
- Human NGFR/p75ECD Rapid ELISA Assay
- 品牌：
- Biosensis
- 货号：
- BEK-2239-1P
- 规格：
- 1 Plate Kit
- 保存建议：
- Store at 2-8°C.
- 背景资料：
- The nerve growth factor (NGF) receptor (NGFR), also known as p75 neurotrophin receptor (p75NTR; TNFRS16; CD271) is a common receptor for the neurotrophins NGF, BDNF, NT-3 and NT-4/5. In neurons, p75NTR mediates a variety of physiological functions including survival, apoptosis, neurite outgrowth and synaptic plasticity. A potential pathological role for p75NTR has become evident in recent years. Altered p75NTR expression levels are implicated in degeneration of spinal motor neurons in human and mouse models of amyotrophic lateral sclerosis (ALS). Importantly, the extracellular domain of p75NTR (p75ECD) is shed from the cell membrane and excreted in urine. Recent findings further suggest that p75ECD could be an early biomarker for ALS in humans, as significantly elevated p75ECD levels are found in urine of ALS patients as compared to healthy controls.
- 货期：
- 4-6周
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
