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Rabbit anti Human Sphingosine Kinase 2, Long Form
Rabbit anti Human Sphingosine Kinase 2, Long Form
- 中文名称：
- Rabbit anti Human Sphingosine Kinase 2, Long Form
- 英文名称：
- Rabbit anti Human Sphingosine Kinase 2, Long Form
- 品牌：
- Nordic-MUbio
- 品牌介绍：
- Nordic公司成立于1964年，是荷兰著名免疫学试剂生产厂商，拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清，以及针对酶的一系列独特的多克隆抗血清。
- 货号：
- X1775P
- 规格：
- 100 µg
- 保存建议：
- -20ºC. Aliquot to avoid freeze/thaw cycles
- 背景资料：
- The long form of sphingosine kinase 2 (Sphk2-L) is a species-specific isoform of the Sphk2 enzyme expressed in human but not in mouse. It is an N-terminal extended form of Sphk2, extended by 36 amino acids. It functions as expected, catalyzing the formation of sphingosine 1-phosphate from sphingosine, however it appears to have a decreased ability to inhibit DNA synthesis as compared to Sphk2-S (short form of Sphk2). Under normal cellular conditions, Sphk2-L does not appear to inhibit DNA synthesis, but under serum deprivation, SphK2-L translocates to the nucleus and accumlates. This accumlation may be involved in the cessation of cell proliferation or apoptosis depending on the cell type.
- 货期：
- 现货/4周
- 来源宿主：
- Rabbit
- 应用：
- ELISA|Western Blotting|Western Blotting
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
别名 / 同义词:Sphk2-L, N-terminal-extended Sphingosine Kinase 2
克隆号/Clone:N/A
亚型/Isotype:N/A
研究领域/Field of Interest:Lipid Mediators
标记/Label:N/A
- 说明书：
