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Rabbit anti Human Trag 3 (Taxol-resistant-associated protein 3)
Rabbit anti Human Trag 3 (Taxol-resistant-associated protein 3)
- 中文名称：
- Rabbit anti Human Trag 3 (Taxol-resistant-associated protein 3)
- 英文名称：
- Rabbit anti Human Trag 3 (Taxol-resistant-associated protein 3)
- 品牌：
- Nordic-MUbio
- 品牌介绍：
- Nordic公司成立于1964年，是荷兰著名免疫学试剂生产厂商，拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清，以及针对酶的一系列独特的多克隆抗血清。
- 货号：
- X1871P
- 规格：
- 50 µg
- 保存建议：
- -20ºC. Aliquot to avoid freeze/thaw cycles
- 背景资料：
- The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.
- 货期：
- 现货/4周
- 来源宿主：
- Rabbit
- 应用：
- Western Blotting|Western blotting
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
别名 / 同义词:Taxol-resistant-associated protein 3
克隆号/Clone:N/A
亚型/Isotype:IgG
研究领域/Field of Interest:Signal Transduction
标记/Label:N/A
- 说明书：
