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Mouse anti Human Cytochrome p450 26A1
Mouse anti Human Cytochrome p450 26A1
- 中文名称:
- Mouse anti Human Cytochrome p450 26A1
- 英文名称:
- Mouse anti Human Cytochrome p450 26A1
- 品牌:
- Nordic-MUbio
- 品牌介绍:
- Nordic公司成立于1964年,是荷兰著名免疫学试剂生产厂商,拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清,以及针对酶的一系列独特的多克隆抗血清。
- 货号:
- X2049M
- 规格:
- 200 µg
- 保存建议:
- -20ºC. Aliquot to avoid freeze/thaw cycles
- 背景资料:
- The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1, also referred to as retinoic acid-4-hydroxylase, is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptors 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli(mcr) mutant zebrafish embryos.
- 货期:
- 现货/4周
- 来源宿主:
- Mouse
- 应用:
- Western Blotting|ELISA|Western Blotting|Immunohistochemistry
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
别名 / 同义词:CYP450 26 (EC 1.14.-.-); Retinoic acid-metabolizing cytochrome; P450 retinoic acid-inactivating 1; P450RAI; hP450RAI; Retinoic acid 4-hydroxylase
克隆号/Clone:F27 P6 A1
亚型/Isotype:IgG2b
研究领域/Field of Interest:Cell Cycle
标记/Label:N/A
- 说明书: