Rabbit anti Human SET, Phosphatase 2A Inhibitor I2PP2A-Rabbit anti Human SET, Phosphatase 2A Inhibitor I2PP2A-一抗检测抗体

: Rabbit anti Human SET, Phosphatase 2A Inhibitor I2PP2A

Rabbit anti Human SET, Phosphatase 2A Inhibitor I2PP2A

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品牌介绍：: Nordic公司成立于1964年，是荷兰著名免疫学试剂生产厂商，拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清，以及针对酶的一系列独特的多克隆抗血清。

背景资料：: Human SET was originally identified as part of the SET-CAN fusion gene produced by a somatic translocation event in a patient with acute undifferentiated leukemia. In developing kidney, SET is highly expressed in the zone of nephron morphogenesis. SET has been shown to be a potent and specific inhibitor of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in regulating cell proliferation and differentiation. SET is also involved in the regulation of renal cell proliferation and tumorigenesis. SET mRNA expression is markedly reduced in cells rendered quiescent by serum starvation, contact inhibition, or differentiation. SET protein expression is also much greater in developing rat and human kidney than in fully differentiated, mature kidney. High levels of SET mRNA and SET protein expression arefound in Wilms' tumor, but not in renal cell carcinoma, adult polycystic kidney disease or in transitional cell carcinoma.

其他：: 别名 / 同义词:SET, SET translocation (myeloid leukemia-associated), Protein SET, Phosphatase 2A inhibitor, I2PP2A, I-2PP2A, Template-activating factor I, TAF-I, HLA-DR-associated protein II, PHAPII, Inhibitor of granzyme A-activated DNase, IGAAD2PP2A; IGAAD; I2PP2A; P
克隆号/Clone:N/A
亚型/Isotype:IgG
研究领域/Field of Interest:Lipid Mediators
标记/Label:N/A