Rabbit anti Human Ceramide Transfer Protein (CERTL)-Rabbit anti Human Ceramide Transfer Protein (CERTL)-一抗检测抗体

: Rabbit anti Human Ceramide Transfer Protein (CERTL)

Rabbit anti Human Ceramide Transfer Protein (CERTL)

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品牌介绍：: Nordic公司成立于1964年，是荷兰著名免疫学试剂生产厂商，拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清，以及针对酶的一系列独特的多克隆抗血清。

背景资料：: CERT mediates the ATP-dependent ER-to-Golgi transfer of ceramide in a non-vesicular manner. The biosynthesis of lipids involves steps that occur in different intracellular compartments. The movement of lipids within these compartments is important in lipid-mediated signalling. Human CERT is identical to a splice variant of human Goodpasture antigen-binding protein (GPBP26).CERT contains a phosphoinositide-binding pleckstrin-homology (PH) domain (which targets CERT to the Golgi by binding phosphatidylinositol-4-phosphate (PtdIns4P)), a middle region, and a putative lipid-transfer-catalysing domain called START. CERT and CERTL can specifically extract ceramide from phospholipid bilayers in a START-domain-dependent manner. CERT interacts with ER membranes and specifically extracts ceramide. CERT catalyses both the specific extraction of ceramide from donor vesicles and its transfer to acceptor vesicles. CERT can associate with the Golgi in a PtdIns4P dependent manner.

其他：: 别名 / 同义词:Lipid-transfer protein CERT, Goodpasture antigen-binding protein isoform 2, GPBP26, GPBP, Collagen type IV alpha-3-binding protein, StAR-related lipid transfer protein 11, StARD11, START domain-containing protein 11, COL4A3BP, STARD11
克隆号/Clone:N/A
亚型/Isotype:IgG
研究领域/Field of Interest:Lipid Mediators
标记/Label:N/A