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Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
- 中文名称：
- Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
- 英文名称：
- Rabbit anti Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking
- 品牌：
- Nordic-MUbio
- 品牌介绍：
- Nordic公司成立于1964年，是荷兰著名免疫学试剂生产厂商，拥有超过1700种针对人、小鼠、猴和大鼠的免疫球蛋白及其亚型的特异性抗血清。公司主要产品包括一系列广泛的针对不同物种血清蛋白的多克隆抗血清，以及针对酶的一系列独特的多克隆抗血清。
- 货号：
- X2740P
- 规格：
- 100 µg
- 保存建议：
- -20ºC. Aliquot to avoid freeze/thaw cycles
- 背景资料：
- This anitbody is made to an epitope that is reported to block the PCSK9-LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low density lipid) metabolism leading to hypercholesterolemia. Additioanlly, PCSK9 may be implicated in the differentiation of cortical neurons and may also play a role in cholesterol homeostasis. Defects in PCSK9 gene are the cause of familial hypercholesterolemia 3 (FH3). The protein is thought to play a central role in cholesterol homeostais
- 货期：
- 现货/4周
- 来源宿主：
- Rabbit
- 应用：
- Western Blotting|ELISA|Western Blotting|ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
别名 / 同义词:Proprotein convertase PC9, Subtilisin/kexin-like protease PC9, Neural apoptosis-regulated convertase 1
克隆号/Clone:N/A
亚型/Isotype:IgG
研究领域/Field of Interest:Lipid Mediators
标记/Label:N/A
- 说明书：
